Main Street Pizza & Cafe Menu

2540 Main St, Irvine, CA 92614, United States
$$$ Italian restaurant
(100 Reviews)
Price Range $10–20

Welcome to Main Street Pizza & Cafe, an Italian treasure located at 2540 Main St, Irvine, CA. This cozy restaurant delights guests with a carefully curated menu that captures the essence of Italian comfort food.

  • Wraps: Savor the Chicken Pesto Wrap, bursting with grilled chicken, provolone, and fresh veggies, or the Turkey Bacon & Avocado Wrap for a hearty crunch.
  • Calzones & Stromboli: Indulge in rich fillings like the Pepperoni Calzone or the Spinach & Artichoke Stromboli, all made with melted mozzarella and ricotta.
  • Desserts: Don’t miss the classic Tiramisu or Cheesecake to end your meal on a sweet note.

Noted for high-quality ingredients, friendly service, and a welcoming atmosphere, Main Street Pizza & Cafe is a must-visit. Customers rave about the fresh pizza, remarkable crust, and accommodating staff, making it a reliable spot for both quick bites and casual dining. Experience the warmth of genuine Italian hospitality here!

Pizza

  • XL Cheese Pizza (18")
    US$21.99
  • Small Cheese Pizza (10")
    US$14.99
  • Large Cheese Pizza (16")
    US$18.99
  • Medium Cheese Pizza (13")
    US$16.99

Hot Pastas

  • Chicken Breast Parmigiana

    Tender breaded chicken topped with mozzarella and Parmesan cheese. Served with spaghetti in marinara.

    US$18.99
  • Linguini & Shrimp

    Shrimp, mushrooms, green peppers and fresh garlic with red or white sauce.

    US$18.99
  • Ravioli

    Cheese or spinach. Choice of marinara, meat, Alfredo, Roasted Red pepper or pesto sauce.

    US$17.99
  • Lasagna

    Six layers of pasta joined by our delicious marinara sauce topped with mozzarella cheese.

    US$17.99
  • Spaghetti With Sausage & Meat Sauce
    US$17.99
  • Fettuccini Alfredo

    Fettuccini smothered in our delicious alfredo sauce.

    US$16.99
  • Pick A Pasta & Sauce
    US$16.99
  • Spaghetti Or Penne With Meatballs

    Served with our homemade meat sauce and meatballs.

    US$20.49
  • Jumbo Cheese Ravioli With Roasted Red Pepper Cream Sauce

    Cheese ravioli, mushrooms, fresh garlic, and roasted red pepper sauce.

    US$17.99
  • Baked Chicken Penne

    Penne pasta with shredded chicken breast, mozzarella cheese, and marinara sauce.

    US$17.99
  • Cajun Pasta

    Fettuccini pasta and chicken breast in a spicy cajun cream sauce.

    US$17.99

Protein Shakes

  • Orange Strawberry

    Orange juice, strawberries and protein.

    US$8.00
  • Banana Peach

    Peaches, banana and protein.

    US$8.00

Side Salads

  • Homemade Tuna Side Salad

    Tuna, finely minced fresh veggies and herbs, lemon juice, mayo and dijon mustard, perched on organic mixed greens.

    US$8.50
  • Almond Chicken Side Salad

    Roasted chicken, celery, red onion, almonds, raisins, green apple, and mayo, perched on organic mixed greens.

    US$8.50
  • Garden Salad Side Salad

    Organic mixed greens, romaine lettuce, carrots, red cabbage, grape tomatoes, cucumber, and bell peppers.

    US$7.99

Cold Sandwiches

  • Moroccan Sandwich

    Turkey, Roasted Red peppers and Red Onion, Arugula, Tomato & Avocado with Chermula sauce.

    US$13.99
  • Turkey Swiss

    Turkey breast, swiss cheese, lettuce and tomato with herb aioli on wheat or ciabatta.

    US$13.99
  • Sicilian Sandwich

    Mortadella, salami, roasted red peppers, red onion, chopped pepperoncini, provolone cheese, lettuce and tomato with our homemade roasted pepper sauce on a baguette.

    US$13.99
  • Vegetarian Sandwich

    Avocado, havarti, and feta cheese, cucumber, spinach, roasted red peppers, lettuce, tomato, onion and pesto sauce on wheat bread.

    US$13.99
  • Roast Beef Sandwich

    Roast beef, pepper jack cheese, lettuce, tomato and horseradish spread on ciabatta bread.

    US$13.99
  • Chicken Pesto

    Roasted chicken, provolone cheese, basil pesto sauce lettuce, tomato and vinaigrette on a baguette.

    US$13.99
  • Tuna Salad Sandwich

    Tasty homemade Tuna salad with Sliced Cucumbers and Havarti Cheese with Spring Mix and tomato.

    US$13.99
  • Ham & Cheese

    Sliced ham and Havarti cheese with herb aioli, lettuce, and tomato on rye or marble rye bread.

    US$13.99
  • Almond Chicken Salad Sandwich

    Tasty homemade chicken with lettuce and tomato.

    US$13.99

Breakfast Sandwiches

  • Vegetarian Burritos

    Potato, avocado, egg, pico de gallo and cheese with homemade salsa.

    US$13.99
  • Breakfast Panini

    Choice of bacon, ham or sausage with egg and cheese on Sourdiugh bread

    US$16.99
  • Bagel Sandwich

    Choice of bacon, ham or sausage with egg and cheese.

    US$15.99
  • Fruit Medley
    US$8.50
  • Breakfast Burritos

    Choice of bacon, sausage, chorizo or ham with egg, roasted potato, and cheese, comes with homemade salsa.

    US$13.99
  • Open Faced Smoked Salmon Bagel Sandwich

    Bagel, smoked salmon, fresh dill, cucumber, cream cheese and capers.

    US$14.99
  • Vegetarian Panini

    Spinach, tomato, roasted red peppers, egg, cheddar cheese and pesto sauce on Sourdough bread.

    US$13.99
  • Hot Oatmeal

    Topped with walnuts, almonds, chia seeds, brown sugar, raisins and cinnamon.

    US$7.50
  • Fruit Parfait
    US$8.50

Wraps

  • Chicken Pesto Wrap

    Grilled chicken, provolone cheese, roasted red peppers, pesto sauce, lettuce and tomato with vinaigrette on a flour tortilla.

    US$14.99
  • Turkey Bacon & Avocado Wrap

    Sliced turkey breast, bacon and swiss cheese with mayo, mustard, avocado, lettuce and tomato on a flour tortilla.

    US$15.99
  • Chicken Caesar Wrap

    Grilled chicken, romaine hearts, tomato, Parmesan cheese and caesar dressing on a wheat tortilla.

    US$14.99
  • Veggie Wrap

    Avocado, havarti, and feta cheese, cucumber, roasted red peppers, lettuce, spinach, tomato, onion and pesto sauce on a wheat tortilla.

    US$14.99
  • Tuna Wrap

    Tuna salad and mixed greens, sliced tomato, cucumber, and havarti cheese on a spinach tortilla.

    US$14.99
  • Almond Chicken Salad Wrap

    homemade chicken salad with lettuce and tomato on a flour tortilla.

    US$14.99

Specialty Drinks

  • Vanilla Latte Medium
    US$4.95
  • Hot Cocoa Medium
    US$4.95
  • Cappuccino Medium
    US$4.95
  • Caramel Latte Medium
    US$4.95
  • Café Latte Medium
    US$4.95
  • Hazelnut Latte Medium
    US$4.95
  • Chai Latte Medium
    US$4.95
  • Café Mocha Medium
    US$4.95

Smoothies

  • Strawberry Splash

    Banana and strawberries.

    US$7.00
  • The Maui

    Pina colada and strawberries.

    US$7.00
  • Morning Glory

    Peaches and banana.

    US$6.00
  • Razzle Dazzle

    Raspberries, banana and orange juice.

    US$6.00
  • Raspberry Royal

    Raspberries and banana.

    US$6.00

Paninis

  • Veggie Panini

    Grilled zucchini and peppers, onion, avocado, tomato, muenster cheese and pesto sauce.

    US$14.99
  • Chicken Pesto Panini

    Roasted chicken, provolone cheese, baby spinach, sun-dried tomato, and basil pesto served on sourdough bread.

    US$14.99
  • Turkey & Bacon Panini

    Turkey, bacon, tomato, Gouda cheese, and herb aioli.

    US$14.99

Specialty Pizzas

  • Vegetarian

    Green peppers, onions, olives, mushrooms, and tomato.

    US$20.99
  • Chunky BBQ Chicken

    Oven-roasted chicken, barbecue sauce, red onions, gouda, blue cheese crumbs, and mozzarella cheese, roasted red pepper and cilantro.

    US$20.99
  • Garlic Chicken With White Sauce

    Alfredo sauce, fresh garlic, grilled chicken and bacon bits.

    US$19.99
  • Garlic Chicken

    Roasted garlic, grilled chicken breast, fresh mushrooms, and mozzarella cheese.

    US$20.99
  • Italian Meatball

    Pizza sauce, sliced meatball, fresh basil and oregano, topped with grape tomatoes and Parmesan cheese.

    US$20.99
  • The Works

    Pepperoni, ham, sausage, salami, green peppers, onions, mushrooms, fresh tomato, and olives.

    US$20.99
  • Greek Style Pizza

    Pizza sauce, mozzarella cheese, sun dried tomatoes, spinach, kalamata olives, feta cheese.

    US$20.99
  • Hawaiian

    Ham and pineapple.

    US$20.99
  • Meat Lovers

    Pepperoni, sausage, ham, salami, ground beef, and bacon.

    US$20.99
  • Margherita

    Fresh roma tomato slices and fresh basil topped with mozzarella and Parmesan cheese.

    US$20.99
  • Artichoke Feta

    Artichoke hearts, tomato, roasted garlic, feta and mozzarella cheese with basil pesto or red pizza sauce.

    US$20.99

Soft Drinks & Juice

  • Snapple
    US$2.95
  • 2 Liter
    US$5.95
  • Canned
    US$1.75
  • Bottled Coke Products

    The cold, refreshing, sparkling classic that America loves.

    US$2.95
  • Apple Juice
    US$2.95
  • Cranberry Juice
    US$2.95
  • Bottled Water
    US$2.95
  • Fresh Squeezed Orange Juice
    US$7.95
  • Fountain
    US$3.60

Hot Sandwiches

  • Sausage

    Mozzarella cheese with sausage links.

    US$14.99
  • Meatball & Cheese

    Meatballs served with our meat sauce and mozzarella cheese.

    US$14.99
  • Chicken Parmesan

    Tender breaded chicken with marinara sauce and mozzarella cheese.

    US$14.99

Bagels & Cream Cheese

  • Bagel & Cream Cheese
    US$4.00
  • Bagels
    US$2.50
  • 4oz Cream Cheese
    US$7.00

Pasta

  • Pasta & Salad
    US$22.99

Desserts

  • Tiramisu
    US$6.00
  • Cheesecake
    US$5.00

Blended Drinks

  • Hazelnut Latte
    US$6.25
  • Latte
    US$6.25
  • Caramel Latte
    US$6.25
  • Mocha
    US$6.25
  • Vanilla Latte
    US$6.25

Calzones

  • Pepperoni Or Sausage

    Mozzarella and ricotta cheese with choice of pepperoni or sausage.

    US$14.99
  • Stromboli

    Mozzarella and Ricotta cheese with ham, pepperoni, Italian sausage and salami.

    US$15.99
  • Spinach & Artichoke

    Mozzarella and Ricotta cheese with spinach, artichokes, and feta cheese.

    US$15.99

Salads

  • South Of The Border

    Crisp romaine lettuce, avocado, cilantro, corn salsa, and cheddar cheese topped with tortilla strips with pepita dressing.

    US$13.99
  • Chinese Chicken Salad

    Organic mixed greens, crisp romaine, chicken, fresh mandarins, peppers, carrots, cilantro, toasted almonds and sesame seeds topped with crisp wontons, served with ginger sesame dressing.

    US$14.99
  • Quinoa Jicama Salad

    Organic mixed greens, red onion, avocado, cilantro, tomato, raisins, jicama, pumpkin seed, cotija cheese and quinoa with mango lime vinaigrette dressing.

    US$14.99
  • Beet Salad

    Organic mixed greens, oven-baked beets, caramelized walnuts, goat cheese, berries with tarragon red wine vinaigrette dressing.

    US$14.99
  • Apple Walnut Salad

    Organic mixed greens, green apple, caramelized walnuts, blue cheese, raisins, berries with our balsamic vinaigrette.

    US$13.99
  • Chipotle Chicken Salad

    Organic mixed greens, romaine, grilled chicken, roasted tricolored peppers, red onion, corn, tomato, fresh cilantro, avocado, and cheddar cheese with cilantro chipotle dressing.

    US$14.99
  • BBQ Chicken Salad

    Grilled chicken with barbecue sauce, lettuce, roasted corn, cilantro, peppers, red cabbage, carrots, pineapple and mozzarella, topped with crispy tortilla strips, served with ranch dressing.

    US$14.99
  • Antipasto Salad

    Romaine's hearts topped with mortadella, salami, ham, kalamata olives, grape tomatoes, peppers, pepperoncini, cucumbers, cheddar, and mozzarella cheese with vinaigrette.

    US$15.99
  • California Salad

    Romaine lettuce with grilled chicken, avocado, grape tomato, blue cheese crumbles and cheddar cheese with choice of ranch or champagne white vinaigrette.

    US$16.99
  • Caesar Salad

    Crisp romaine hearts lettuce and Parmesan cheese with caesar dressing.

    US$12.99

Appetizers

  • French Fries
    US$3.99
  • Garlic Bread

    Order of five.

    US$7.00
  • Buffalo Wings Full Dz
    US$19.00
  • Buffalo Wings Half Dz
    US$14.49